Prognostic Factors of Retinopathy of Prematurity

Of 782 premature babies who had been examed, 105(13.4%) were found to have retinopathy of prematurity(ROP). Between normal group and ROP group, there was statistically significant difference in birth weight, gestational age, duration of oxygen therapy and maximum arterial oxygen concentration. Between the group of regression(stage 1.2 to normal) and the group of progression(stage 1.2 to prethreshold disease) there was statistically significant difference in birth weight, gestational age and the circumferential extent of avascular zone. The 35% of prethreshold ROP eyes progressed to threshold ROP and mean interval from prethreshold to threshold ROP was 3.6 weeks.